The original paper describing the trial is Hammer, S. M., Katzenstein, D. A., Hughes, M. D., Gundaker, H., Schooley, R. T., Haubrich, R. H., Henry, W. K., Lederman, M. M., Phair, J. P., Niu, M., Hirsch, M. S., and Merigan, T. C., for the Aids Clinical Trials Group Study 175 Study Team (1996). A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 counts from 200 to 500 per cubic millimeter. The New England Journal of Medicine, 1081-1089.
Linear regression of response = cd4 count at 20 +- 5 weeks (cd420) was used in Tsiatis, A.A., Davidian, M., Zhang, M., and Lu, X. (2008), "Covariate adjustment for two-sample treatment comparisons in randomized clinical trials: A principled yet flexible approach," Statistics in Medicine.
Cox regression of response = time to death (event) was used in Lu X, Tsiatis AA (2008), "Improving the efficiency of the logrank test using auxiliary covariates," Biometrika.
In the text file above, the variables are named
censor censoring indicator = 1 if dead, = 0 if censored
event event time
age age (yrs) at baseline
wtkg weight (kg) at baseline
hemo hemophilia (0=no, 1=yes)
homo homosexual activity (0=no, 1=yes)
drugs history of IV drug use (0=no, 1=yes)
karnof Karnofsky score (on a scale of 0-100)
oprior Non-ZDV antiretroviral therapy pre-175 (0=no, 1=yes)
z30 ZDV in the 30 days prior to 175 (0=no, 1=yes)
zprior ZDV prior to 175 (0=no, 1=yes)
preanti # days pre-175 anti-retroviral therapy
race race (0=White, 1=non-white)
gender gender (0=F, 1=M)
str2 antiretroviral history (0=naive, 1=experienced)
strat antiretroviral history stratification
(1='Antiretroviral Naive',2='> 1 but <= 52 weeks of prior
antiretroviral therapy',3='> 52 weeks)
symptom symptomatic indicator (0=asymp, 1=symp)
cd40 baseline cd4
cd420 cd4 count at 20 +- 5 weeks
cd496 cd4 count at 96 +- 5 weeks (missing for a lot of subjects)
r missingness indicator for cd496
cd80 baseline cd8 count
cd820 cd8 count at 20 +- 5 weeks